Ureaplasma urealyticum in the urethra of healthy men.

Abstract
Healthy married white men (19) had samples of 1st-voided urine cultured for U. urealyticum at weekly intervals for 17 consecutive wk. Of these, 63% harbored U. urealyticum in their urine on at least 1 occasion; in 40% of the men with positive culture results ureaplasmas were isolated from 90% of samples. Those men whose specimens were frequently culture-positive had notably higher titers for U. urealyticum than those whose specimens were less frequently positive. There was no significant correlation between the number of leukocytes in the urinary sediment and the amount of U. urealyticum in the corresponding urine specimens, although ureaplasma-positive urine specimens tended to contain slightly more leukocytes than ureaplasma-negative samples. Titer rises of U. urealyticum 4-fold or higher in urine samples were not associated with urethral signs or symptoms. One man with a presumably primary infection developed dysuria. Of 65 strains of U. urealyticum serotyped, types 2 and 3 predominated; the serotype found in each patient was fairly constant.