The Potentiating Effect of ACTH and of Cortisone on Pressor Response to Intravenous Infusion of L-Nor-Epinephrine.
- 1 October 1951
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 78 (1) , 28-31
- https://doi.org/10.3181/00379727-78-18962
Abstract
The pressor response to an intraven. infusion of 2.1-13.9 [mu]g./min. of l-nor-epinephrine was studied, using a constant rate infusion apparatus, in 3 patients before and during admn. of ACTH and cortisone. Striking potentiation of the blood pressure response to nor-epinephrine was noted within 24 hours after admn. of 90-180 mg ACTH daily or 150-200 mg cortisone daily. The potentiating effect disappeared within 36 hours after the omission of these agents.Keywords
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