Coincidental finding of May‐Hegglin anomaly in a patient with end‐stage renal failure
- 11 July 1992
- journal article
- case report
- Published by Wiley in American Journal of Hematology
- Vol. 40 (3) , 216-221
- https://doi.org/10.1002/ajh.2830400311
Abstract
We present two cases of May‐Hegglin anomaly incidentally discovered in a patient and his brother during investigation of the patient for end‐stage renal failure and workup for renal transplantation. Routine laboratory tests were performed and included a basically normal clotting profile. Ultrastructural studies of the May‐Hegglin inclusions proved diagnostic, findings were compared with those of two similar granulocyte inclusion bodies, and nomenclature discrepancies that still exist in most references are again emphasized. The finding of the May‐Hegglin anomaly in our patient appears to be incidental to the underlying renal disease. A successful renal transplant has been carried out in this patient.We now report on a patient and his brother in which the MHA was discovered during workup of the patient for end‐stage renal failure and renal transplantation. No association between the underlying renal disease and the MHA could be demonstrated.Keywords
This publication has 15 references indexed in Scilit:
- Successful Splenectomy in May-Hegglin Anomaly: Report of a Case with Platelet Kinetic StudiesActa Haematologica, 1989
- Hereditary Nephritis Associated with May-Hegglin AnomalyNephron, 1981
- Platelet Function, Ultrastructure, and Survival in the May-Hegglin AnomalyAmerican Journal of Clinical Pathology, 1980
- Thrombocytopenia, macrothrombocytopathia, nephritis and deafnessThe American Journal of Medicine, 1976
- May-Hegglin Anomaly: A Defect in Megakaryocyte Fragmentation?British Journal of Haematology, 1974
- The May-Hegglin AnomalyActa Haematologica, 1974
- The Inclusions of the May-Hegglin Anomaly and Dohle Bodies of Infection: an Ultrastructural ComparisonBritish Journal of Haematology, 1972
- Hereditary macrothrombocytopathia, nephritis and deafnessThe American Journal of Medicine, 1972
- The May-Hegglin Anomaly: Ultrastructure of the Granulocytic InclusionAmerican Journal of Clinical Pathology, 1971
- May-Hegglinsche AnomalieActa Haematologica, 1969