Penicillinase Production in Community Strains of Staphylococcus Aureus

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Abstract
A survey of penicillinase production in 406 strains of S. aureus isolated from wounds in the county of Uppsala [Sweden] in 1975 showed that 76% of strains from inpatients produced penicillinase compared to 69% of the outpatient strains. The frequency of penicillinase production in S. aureus strains from surgical staff was 59%. Of strains from school children, 51%, and 38% of strains from healthy adults produced penicillinase. Ordinary penicillinase-sensitive penicillin should apparently not be used for treating infections in outpatients unless the isolated strain is penicillinase-negative.