Correlation of Brain Metabolism and Function by the Use of a Brain Perfusion Method In Situ

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Abstract
The scope of this paper is limited to such aspects of brain metabolism and functions as have been investigated to date by perfusion methods, and to the correlation of findings by this method, with the results obtained by other approaches. Some space is devoted to the technique of brain perfusion in vivo; then to conditions affecting cerebral blood flow and oxygen consumption; to chemical inter-relationship between brain and liver; to pyrimidine and purine nucleotides as co-factors in brain metabolism; to glucose transfer from blood to brain; survival of brain in absence of glucose; fate of glucose in brain; utilization of lipids; protein utilization; and endogenous substrates metabolized during activity.

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