1,4:3,6-Dianhydrohexitol Nucleosides

Abstract
Novel types of nucleoside analogues, being potential anticancer and antiviral candidates and exhibiting a 1,4:3,6-dianhydrohexitol moiety as the carbohydrate part of the molecule, are described. The synthesis has been performed by reacting the appropriate chloromethylated, protected dianhydrohexitol with silylated bases.