STUDIES OF AMNIOTIC MEMBRANES

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Abstract
Tensile strength, mucopolysaccharide deposits, hexosamine and collagen contents of membranes were studied in mature and premature deliveries. Membrane tensile strength, which was found to vary between 50 and 500 g/cm, is significantly higher in membranes of premature deliveries as compared to mature deliveries. An inverse correlation between tensile strength and foetal weight was observed. Acid mucopolysaccharides are more frequently and abundantly found in membranes as pregnancy progresses. A similar tendency was found with hexosamine content of the membranes. Collagen values did not vary significantly in mature and premature deliveries. A significant correlation was found between the reduction of collagen-hexosamine ratio and reduction in membrane tensile strength. The possibility that this change is related to placental dysfunction and associated with hormonal imbalance has been discussed.