Kinase-active Interleukin-1 Receptor-associated Kinases Promote Polyubiquitination and Degradation of the Pellino Family

This publication has 29 references indexed in Scilit:

• A critical role for IRAK4 kinase activity in Toll-like receptor–mediated innate immunity
  The Journal of Experimental Medicine, 2007
• Ubiquitin-conjugating enzyme Ubc13 is a critical component of TNF receptor-associated factor (TRAF)-mediated inflammatory responses
  Proceedings of the National Academy of Sciences, 2007
• Pellino proteins are more than scaffold proteins in TLR/IL‐1R signalling: A role as novel RING E3–ubiquitin‐ligases
  FEBS Letters, 2006
• Sequential Autophosphorylation Steps in the Interleukin-1 Receptor-associated Kinase-1 Regulate its Availability as an Adapter in Interleukin-1 Signaling
  Journal of Biological Chemistry, 2004
• IRAK-M Is a Negative Regulator of Toll-like Receptor Signaling
  Cell, 2002
• Innate Immune Recognition
  Annual Review of Immunology, 2002
• Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4
  Nature, 2002
• IRAK-mediated Translocation of TRAF6 and TAB2 in the Interleukin-1-induced Activation of NFκB
  Journal of Biological Chemistry, 2001
• Activation of the IκB Kinase Complex by TRAF6 Requires a Dimeric Ubiquitin-Conjugating Enzyme Complex and a Unique Polyubiquitin Chain
  Published by Elsevier ,2000
• A Multiubiquitin Chain Is Confined to Specific Lysine in a Targeted Short-Lived Protein
  Science, 1989