The ETS-domain transcription factor family
Top Cited Papers
- 1 November 2001
- journal article
- review article
- Published by Springer Nature in Nature Reviews Molecular Cell Biology
- Vol. 2 (11) , 827-837
- https://doi.org/10.1038/35099076
Abstract
ETS-domain transcription-factor networks represent a model for how combinatorial gene expression is achieved. These transcription factors interact with a multitude of co-regulatory partners to elicit gene-specific responses and drive distinct biological processes. These proteins are controlled by a complex series of inter and intramolecular interactions, and signalling pathways impinge on these proteins to further regulate their action.Keywords
This publication has 109 references indexed in Scilit:
- The ternary complex factor Net contains two distinct elements that mediate different responses to MAP kinase signalling cascadesOncogene, 2000
- Id helix–loop–helix proteins inhibit nucleoprotein complex formation by the TCF ETS-domain transcription factorsThe EMBO Journal, 1999
- The Structure of GABPα/β: An ETS Domain- Ankyrin Repeat Heterodimer Bound to DNAScience, 1998
- Pip, a lymphoid-restricted IRF, contains a regulatory domain that is important for autoinhibition and ternary complex formation with the Ets factor PU.1.Genes & Development, 1996
- Modulation of Transcription Factor Ets-1 DNA Binding: DNA-Induced Unfolding of an α HelixScience, 1995
- Solution structure of the ets domain of Fli-1 when bound to DNANature Structural & Molecular Biology, 1994
- Requirement of Transcription Factor PU.1 in the Development of Multiple Hematopoietic LineagesScience, 1994
- The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domainCell, 1993
- Evolution of the ets Gene FamilyBiochemical and Biophysical Research Communications, 1993
- Ets-related protein Elk-1 is homologous to the c-fos regulatory factor p62TCFNature, 1991