R Plasmids in Streptococcus agalactiae (Group B)
- 1 November 1976
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 10 (5) , 795-801
- https://doi.org/10.1128/aac.10.5.795
Abstract
Two plasmids determining resistance to tetracycline (RIP500) and to chloramphenicol, erythromycin, lincomycin, and pristinamycin I (RIP501) were isolated from a strain of Streptococcus agalactiae . The frequency-of-resistance loss is very low for RIP500 (4 ) but higher for RIP501 (the efficiency was dependent upon the curing agents and incubation temperature and varied between 0.5 and 96%). Derivatives susceptible to all drugs were also obtained. RIP500 and RIP501 have similar molecular weights (17.9 × 10 6 and 20 × 10 6 , respectively) and represent different percentages of total deoxyribonucleic acid (0.4 and 4%, respectively). The number of copies of RIP500 and RIP501 per cell is different, and these plasmids are likely replicated under different kinds of control (stringent and/or relaxed). No plasmid deoxyribonucleic acid was found in a derivative of strain B96 susceptible to all drugs.Keywords
This publication has 18 references indexed in Scilit:
- The Elimination of Urease Activity in Streptococcus faecium as Evidence for Plasmid-coded UreaseJournal of General Microbiology, 1976
- Plasmid-Determined Resistance to Erythromycin: Comparison of Strains of Streptococcus faecalis and Streptococcus pyogenes with Regard to Plasmid Homology and Resistance InducibilityAntimicrobial Agents and Chemotherapy, 1975
- Artificial Elimination of Drug Resistance from Group A Beta-Hemolytic StreptococciAntimicrobial Agents and Chemotherapy, 1975
- Genetics of resistance to macrolide antibiotics and lincomycin in natural isolates of Streptococcus pyogenesMolecular Genetics and Genomics, 1974
- Identification of two plasmids determining resistance to tetracycline and to erythromycin in group D StreptococcusMolecular Genetics and Genomics, 1974
- Characterization of a Plasmid Determining Resistance to Erythromycin, Lincomycin, and Vernamycin B α in a Strain of Streptococcus pyogenesAntimicrobial Agents and Chemotherapy, 1974
- Resistance of Group A Beta-Hemolytic Streptococci to Lincomycin and ErythromycinAntimicrobial Agents and Chemotherapy, 1972
- Bacterial Genome Sizes Determined by DNA Renaturation StudiesJournal of General Microbiology, 1970
- Susceptibility of Group D Streptococcus (Enterococcus) to 21 Antibiotics In Vitro, with Special Reference to Species DifferencesThe Lancet Healthy Longevity, 1969
- Studies with Escherichia coli Sex FactorsCold Spring Harbor Symposia on Quantitative Biology, 1968