Predicting oral absorption of drugs: a case study with a novel class of antimicrobial agents.
- 1 January 2003
- journal article
- research article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 20 (8) , 1149-1155
- https://doi.org/10.1023/a:1025084527878
Abstract
No abstract availableKeywords
This publication has 16 references indexed in Scilit:
- Correlation of Gene Expression of Ten Drug Efflux Proteins of the ATP-Binding Cassette Transporter Family in Normal Human Jejunum and in Human Intestinal Epithelial Caco-2 Cell MonolayersThe Journal of Pharmacology and Experimental Therapeutics, 2001
- Determination of the Aqueous Solubility of Drugs Using a Convenient 96-Well Plate-Based AssayDrug Development and Industrial Pharmacy, 2001
- Substituent Effects on the Antibacterial Activity of Nitrogen−Carbon-Linked (Azolylphenyl)oxazolidinones with Expanded Activity Against the Fastidious Gram-Negative Organisms Haemophilus influenzae and Moraxella catarrhalisJournal of Medicinal Chemistry, 2000
- Role of the Development Scientist in Compound Lead Selection and OptimizationJournal of Pharmaceutical Sciences, 2000
- Compound optimization in early- and late-phase drug discovery: acceptable pharmacokinetic properties utilizing combined physicochemical, in vitro and in vivo screens.2000
- The Pharmacologic and Bacteriologic Properties of Oxazolidinones, a New Class of Synthetic AntimicrobialsPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1998
- Evaluation of Biocoat® Intestinal Epithelium Differentiation Environment (3-Day Cultured Caco-2 Cells) as an Absorption Screening Model with Improved ProductivityPharmaceutical Research, 1997
- Guidance in the Setting of Drug Particle Size Specifications to Minimize Variability in AbsorptionPharmaceutical Research, 1996
- Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cellsBiochemical and Biophysical Research Communications, 1991
- Caco-2 Cell Monolayers as a Model for Drug Transport Across the Intestinal MucosaPharmaceutical Research, 1990