To Refer or Not to Refer: Factors that Affect Primary Care Provider Referral of Patients with Cancer to Clinical Treatment Trials

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Abstract
Despite breakthroughs in experimental cancer treatment, relatively few patients participate in cancer clinical treatment trials (CCTTs). Primary care providers (PCPs) have a strong influence on patients' decisions to participate in a CCTT. To determine factors that influence PCP referral of patients to CCTTs, we conducted a descriptive survey of 571 Michigan PCPs. Attendance at CCTT educational sessions consistently predicted referral. Provider attitudes regarding CCTT perceived knowledge, access, and comfort with responsibilities when patients were in a CCTT also predicted referral. Findings support allocating funds to provide CCTT education to PCPs to increase numbers of patients willing to participate in CCTTs.