Preparation and Characterization of Nε-(2,3-Dihydroxypropyl)-L-lysine and its Phenylthiohydantoin Derivative

Abstract
Convenient methods of preparative synthesis of N.epsilon.-(2,3-dihydroxypropyl)-L-lysine and its phenylthiohydantoin derivative are described. The former compound was characterized by elemental analysis, melting point, and ion-exchange chromatography and the latter by elemental analysis, melting point, UV-spectrum, HPLC and thin-layer chromatography. This study was performed for investigations of lysine residues in proteins.