Preparation and Characterization of Nε-(2,3-Dihydroxypropyl)-L-lysine and its Phenylthiohydantoin Derivative
- 1 January 1987
- journal article
- research article
- Published by Walter de Gruyter GmbH in Biological Chemistry Hoppe-Seyler
- Vol. 368 (2) , 1489-1494
- https://doi.org/10.1515/bchm3.1987.368.2.1489
Abstract
Convenient methods of preparative synthesis of N.epsilon.-(2,3-dihydroxypropyl)-L-lysine and its phenylthiohydantoin derivative are described. The former compound was characterized by elemental analysis, melting point, and ion-exchange chromatography and the latter by elemental analysis, melting point, UV-spectrum, HPLC and thin-layer chromatography. This study was performed for investigations of lysine residues in proteins.This publication has 12 references indexed in Scilit:
- Application of reductive dihydroxypropylation of amino groups of proteins in primary structural studies: identification of phenylthiohydantoin derivative of ε-dihydroxypropyl-lysine residues by high-performance liquid chromatographyJournal of Chromatography A, 1984
- ALTERNATIVE REDUCING AGENTS FOR REDUCTIVE METHYLATION OF AMINO GROUPS IN PROTEINSInternational Journal of Peptide and Protein Research, 1981
- Identification of the Phenylthiohydantoin Derivatives of Amino Acids by High Pressure Liquid Chromatography, Using a Ternary, Isocratic Solvent SystemHoppe-Seyler´s Zeitschrift Für Physiologische Chemie, 1980
- EXTENSIVE MODIFICATION OF PROTEIN AMINO GROUPS BY REDUCTIVE ADDITION OF DIFFERENT SIZED SUBSTITUENTSInternational Journal of Peptide and Protein Research, 1979
- HEMOGLOBINS .21. SEQUENCE-ANALYSIS OF PORCINE HEMOGLOBIN1978
- Inhibition of erythrocyte sickling in vitro by DL-glyceraldehyde.Proceedings of the National Academy of Sciences, 1977
- REDUCTIVE ALKYLATION OF PROTEINS WITH AROMATIC ALDEHYDES AND SODIUM CYANOBOROHYDRIDEInternational Journal of Peptide and Protein Research, 1974
- Reductive alkylation of amino groups in proteinsBiochemistry, 1968
- Identity of Synthetic N6-β-Glyceryllysine and the C14-Labeled Amino Acid Obtained on Sodium Borohydride Reduction and Hydrolysis of a Complex from C14-Fructose 6-Phosphate-Transaldolase InteractionJournal of the American Chemical Society, 1963