Allergic Granulomatosis with Massive Gastric Involvement

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Abstract
ALTHOUGH granulomatous reactions had been observed in association with allergic states, it was Churg and Strauss1 who, in 1951, defined allergic granulomatosis as a clinicopathological syndrome. Asthma preceded the onset of the disease, which was usually characterized by weight loss, fever, anemia, a marked increase in blood eosinophilic leukocytes and a declivitous course resulting in death. The histologic hallmark was the presence of distinctive allergic granulomas in connective and muscular tissues, particularly of lung, cardiovascular system and kidney and subcutaneously. These were usually microscopic in size, but some of them had become confluent, forming gross nodules.A variety of granulomatous . . .

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