SOME FACTORS IN SECRETION BY SUBMAXILLARY GLANDS OF CATS

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Abstract
The optimal frequency for electrical stimulation of the submaxillary glands of cats anesthetised with Dial was about 9 per sec. Long-continued stimulation of the gland at frequencies above 28.6 shocks per sec. gave a series of changes in rate of secretion analogous to the changes in tension of a muscle under similar conditions. Pilocarpine stimulation of the submaxillary gland produced a greater saliva flow for a given blood flow than did chorda stimulation. This is believed to explain in part the exhaustion of the K content of the gland during secretion after pilocarpine adm. With both electrical and pilocarpine stimulations there was a linear relationship between superbasal blood flow and saliva production. The K conc. in the saliva increased markedly at rates of secretion below about 0.03 ml. per min. This could be due either to reabsorption of water from the ducts or to the entrance of a greater proportion of intracellular water high in K into the saliva.

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