Leukemia‐associated Rho guanine nucleotide exchange factor (LARG) links heterotrimeric G proteins of the G12 family to Rho
Open Access
- 21 November 2000
- journal article
- Published by Wiley in FEBS Letters
- Vol. 485 (2-3) , 183-188
- https://doi.org/10.1016/s0014-5793(00)02224-9
Abstract
A putative guanine nucleotide exchange factor (GEF), termed leukemia‐associated RhoGEF (LARG), was recently identified upon fusion to the coding sequence of the MLL gene in acute myeloid leukemia. Al...Keywords
This publication has 26 references indexed in Scilit:
- The Role of Rho in G Protein-Coupled Receptor Signal TransductionAnnual Review of Pharmacology and Toxicology, 2000
- p115 RhoGEF, a GTPase Activating Protein for Gα 12 and Gα 13Science, 1998
- Direct Stimulation of the Guanine Nucleotide Exchange Activity of p115 RhoGEF by Gα 13Science, 1998
- Signal transduction by the c-Jun N-terminal kinase (JNK) — from inflammation to developmentCurrent Opinion in Cell Biology, 1998
- Dbl family proteinsBiochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1997
- Protein–protein interactions: PDZ domain networksCurrent Biology, 1996
- Gα12 and Gα13 Stimulate Rho-dependent Stress Fiber Formation and Focal Adhesion AssemblyJournal of Biological Chemistry, 1995
- The small GTP-binding proteins Rac1 and Cdc42regulate the activity of the JNK/SAPK signaling pathwayCell, 1995
- Potent Transforming Activity of the G13 α Subunit Defines a Novel Family of OncogenesBiochemical and Biophysical Research Communications, 1994
- Proteins regulating Ras and its relativesNature, 1993