Characterization of Osteoblast-like Cells from Fetal Rat Calvaria

1 November 1980

journal article
research article
Published by SAGE Publications in Journal of Dental Research

Vol. 59 (11) , 2006-2013
https://doi.org/10.1177/00220345800590111901

Abstract

An improved method is described for the isolation of osteoblast-like cells from fetal rat calvaria. The cells are mononuclear, 8.3μ in diameter, alkaline phosphate positive, and possess rough endoplasmic reticulum, mitochondria, Golgi, and cytoplasmic processes. Isolated bone cells synthesize collagen and cholesterol, grow to confluency in primary culture, and respond to hormonal stimulation.

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