Structural Insight into Modest Binding of a Non-PXXP Ligand to the Signal Transducing Adaptor Molecule-2 Src Homology 3 Domain
Open Access
- 1 November 2003
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 278 (48) , 48162-48168
- https://doi.org/10.1074/jbc.m306677200
Abstract
No abstract availableKeywords
This publication has 36 references indexed in Scilit:
- Gads/Grb2-Mediated Association with LAT Is Critical for the Inhibitory Function of Gab2 in T CellsMolecular and Cellular Biology, 2003
- A High-Affinity Arg-X-X-Lys SH3 Binding Motif Confers Specificity for the Interaction between Gads and SLP-76 in T Cell SignalingCurrent Biology, 2002
- A Combined Experimental and Computational Strategy to Define Protein Interaction Networks for Peptide Recognition ModulesScience, 2002
- Novel recognition mode between Vav and Grb2 SH3 domainsThe EMBO Journal, 2001
- The C-terminal SH3 domain of the adapter protein Grb2 binds with high affinity to sequences in Gab1 and SLP-76 which lack the SH3-typical P-x-x-P core motifOncogene, 2001
- A Deubiquitinating Enzyme UBPY Interacts with the Src Homology 3 Domain of Hrs-binding Protein via a Novel Binding Motif PX(V/I)(D/N)RXXKPJournal of Biological Chemistry, 2000
- Identification of an Atypical Grb2 Carboxyl-terminal SH3 Domain Binding Site in Gab Docking Proteins Reveals Grb2-dependent and -independent Recruitment of Gab1 to Receptor Tyrosine KinasesJournal of Biological Chemistry, 2000
- UBPY: a growth-regulated human ubiquitin isopeptidaseThe EMBO Journal, 1998
- Structural determinants of peptide-binding orientation and of sequence specificity in SH3 domainsNature, 1994
- Identification of a Ten-Amino Acid Proline-Rich SH3 Binding SiteScience, 1993