Recurrent Churg-Strauss vasculitis. With exophthalmos, hearing loss, nasal obstruction, amyloid deposits, hyperimmunoglobulinemia E, and circulating immune complexes
- 1 September 1981
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of internal medicine (1960)
- Vol. 141 (10) , 1363-1365
- https://doi.org/10.1001/archinte.141.10.1363
Abstract
Churg-Strauss vasculitis in remission for 4.5 yr recurred, with new, previously undescribed features, after a lapse in corticosteroid therapy. Bilateral exophthalmos, unilateral hearing loss and nasal obstruction accompanied fever, severe asthma and palpable purpura. Leukocytosis with eosinophilia, elevated ESR, hyperimmunoglobulinemia E and pulmonary infiltrates were seen again. Circulating immune complexes were detected, and microamyloid deposits were found in the conjunctiva and skin. All clinical and laboratory manifestations responded to corticosteroid therapy. Monitoring the levels of IgE may add a diagnostic and prognostic feature to the classification of necrotizing vasculitides.This publication has 3 references indexed in Scilit:
- The Spectrum of VasculitisAnnals of Internal Medicine, 1978
- Response to corticosteroids in the hypereosinophilic syndrome. Association with increased serum IgE levelsArchives of internal medicine (1960), 1978
- Necrotizing Vasculitis After Acute Serous Otitis MediaAnnals of Internal Medicine, 1974