Evidence that SE is distal to LU on chromosome 19q
- 1 May 1989
- journal article
- research article
- Published by Wiley in Transfusion
- Vol. 29 (4) , 304-305
- https://doi.org/10.1046/j.1537-2995.1989.29489242794.x
Abstract
Analysis of a family informative for chromosome 19 loci establishes that the Lutheran blood group locus (LU) lies between the third component of human complement (C3) and the secretor loci (SE). Previously published lod scores for C3:LU are increased from 2.94 to 3.80. The linkage relationship (.cxa.z and .cxa..theta.) between C3, LU, and SE are examined,and the proposed order and approximate genetic distances are determined to be: pter - - C3 - 10.6cM - cen - 7.4cM - LU - 9cM - SE -- qter.This publication has 4 references indexed in Scilit:
- The Colton blood group locusTransfusion, 1988
- The locus for apolipoprotein E (apoE) is close to the Lutheran (Lu) blood group locus on chromosome 19Human Genetics, 1984
- Gentics and linkage relationships of the C3 polymorphism: discovery of C3‐Se linkage and assignment of LES‐C3‐DM‐Se‐PEPD‐Lu synteny to chromosome 19Clinical Genetics, 1983
- LUTHERAN AND SECRETOR LOCI - GENETIC LINKAGE ANALYSIS1977