In vitro susceptibility ofAeromonas caviae, Aeromonas hydrophila andAeromonas sobria to fifteen antibacterial agents

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Abstract
In vitro testing of the activity of 15 antibacterial agents against 522 clinical isolates ofAeromonas species demonstrated some species-associated trends. Amoxicillin plus clavulanic acid was effective against approximately 45% ofAeromonas caviae andAeromonas hydrophila, but allAeromonas sobria isolates were resistant. Aztreonam, piperacillin and mezlocillin were highly active against all the strains ofAeromonas tested. Ticarcillin was equally effective againstAeromonas caviae andAeromonas hydrophila, but more than 50% ofAeromonas sobria isolates were resistant. The latter species was more susceptible to cephalosporins thanAeromonas hydrophila andAeromonas caviae. Chloramphenicol, tetracycline and trimethoprim-sulfamethoxazole were extremely active against all threeAeromonas species, likewise ofloxacin and ciprofloxacin. Aztreonam, third-generation cephalosporins, chloramphenicol and the quinolones can thus be considered for therapy of infections whenAeromonas is implicated.

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