THE ROLE OF ALKALINE PHOSPHATASE IN INTESTINAL ABSORPTION: II. THE EFFECTS OF VARIOUS CARBOHYDRATES ON LEVELS OF THE ENZYME IN INTESTINAL MUCOSA

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Abstract
Adult male rats were deproved of food for 5 days. These animals were then offered cellulose or cellulose mixed with 1 of 7 other carbohydrates. Six hours after food was placed before them, the animals were sacrificed, and a portion of the intestine from each rat was homogenized. Intestinal alkaline phosphatase estimations indicated (1) that the activity of the enzyme was increased significantly by the ingestion of glucose, galactose, fructose, and mannose, whereas (2) there was not a statistically significant elevation of the enzyme level from feeding cellulose, arabinose, xylose, or sucrose. Apparently alkaline phosphatase is involved in the intestinal absorption of glucose, galactose, fructose and mannose.