Randomized Clinical Study of Thiopental Loading in Comatose Survivors of Cardiac Arrest
- 13 February 1986
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 314 (7) , 397-403
- https://doi.org/10.1056/nejm198602133140701
Abstract
After restoration of spontaneous circulation and adequate oxygenation, 262 comatose survivors of cardiac arrest were randomly assigned to receive standard brain-oriented intensive care or the same standard therapy plus a single intravenous loading dose of thiopental (30 mg per kilogram of body weight). The study was designed to have an 80 percent probability of detecting a 20 percent reduction in the incidence of permanent postischemic cerebral dysfunction.This publication has 26 references indexed in Scilit:
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