Biochemistry and Genetics of Insect Resistance to Bacillus thuringiensis
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- 1 January 2002
- journal article
- review article
- Published by Annual Reviews in Annual Review of Entomology
- Vol. 47 (1) , 501-533
- https://doi.org/10.1146/annurev.ento.47.091201.145234
Abstract
▪ Abstract Bacillus thuringiensis (Bt) is a valuable source of insecticidal proteins for use in conventional sprayable formulations and in transgenic crops, and it is the most promising alternative to synthetic insecticides. However, evolution of resistance in insect populations is a serious threat to this technology. So far, only one insect species has evolved significant levels of resistance in the field, but laboratory selection experiments have shown the high potential of other species to evolve resistance against Bt. We have reviewed the current knowledge on the biochemical mechanisms and genetics of resistance to Bt products and insecticidal crystal proteins. The understanding of the biochemical and genetic basis of resistance to Bt can help design appropriate management tactics to delay or reduce the evolution of resistance in insect populations.Keywords
This publication has 144 references indexed in Scilit:
- Histopathological Effects and Growth Reduction in a Susceptible and a Resistant Strain of Heliothis virescens (Lepidoptera: Noctuidae) Caused by Sublethal Doses of Pure Cry1A Crystal Proteins from Bacillus thuringiensisBiocontrol Science and Technology, 1999
- Bacillus thuringiensisCrystal Proteins CRY1Ab and CRY1Fa Share a High Affinity Binding Site inPlutella xylostella(L.)Biochemical and Biophysical Research Communications, 1996
- Transgenic broccoli expressing aBacillus thuringiensis insecticidal crystal protein: Implications for pest resistance management strategiesMolecular Breeding, 1995
- Immunohistochemical Detection of Binding of Cryia Crystal Proteins of Bacillus thuringiensis in Highly Resistant Strains of Plutella xylostella (L.) from HawaiiBiochemical and Biophysical Research Communications, 1995
- Inheritance of resistance to a Bacillus thuringiensis toxin in a field population of diamondback moth (Plutella xylostella)Pesticide Science, 1995
- Altered Protoxin Activation by Midgut Enzymes from a Bacillus thuringiensis Resistant Strain of Plodia interpunctellaBiochemical and Biophysical Research Communications, 1994
- Bacillus thuringiensisresistant colorado potato beetle and transgenic plants: Some operational and ecological implications for deploymentBiocontrol Science and Technology, 1994
- Lack of cross‐resistance to otherBacillus thuringiensiscrystal proteins in a population ofPlutella xylostellahighly resistant to cryia(b)Biocontrol Science and Technology, 1994
- Instability of resistance toBacillus thuringiensisBiocontrol Science and Technology, 1994
- The Complex Genetic Basis of Resistance toBacillus thuringiensisToxin in InsectsBiocontrol Science and Technology, 1994