Analysis of the fragile-X chromosome: localization and detection of the fragile site in high resolution preparations
- 1 March 1985
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 69 (3) , 209-211
- https://doi.org/10.1007/bf00293026
Abstract
Fragile X chromosome preparations were analyzed at levels of up to 850 bands per haploid set. We were able to consistently sublocalize the Xqter fragile site to band Xq27.3 using high-resolution methods. Chromosome length versus the frequency of fragile X expression was also compared. The fragile site appeared at a higher percentage in more condensed chromosome preparations. The importance of this finding is that high-resolution chromosome preparations do not optimize fragile-X detection.This publication has 18 references indexed in Scilit:
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