Clinical and pathological changes caused by the interaction of lasalocid and chloramphenicol in broiler chickens

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Abstract
Uncommon and abnormal gait, characterised by toe walking and progressive leg weakness, was observed in a large broiler flock in Israel. Identical clinical signs were reproduced when young chicks received feed supplemented with lasalocid (Abatec‐Roche), and chloramphenicol at normal recommended levels, for 12 days or more. The clinical and pathological findings suggest a neuromuscular toxic effect of lasalocid‐chloramphenicol interaction in broiler chicks. To our best knowledge this is the first report on the toxic effect caused by the combination of lasalocid and chloramphenicol.

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