Recovery of Thiamine Injected into the Rat Cecum.
- 1 April 1962
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 109 (4) , 776-778
- https://doi.org/10.3181/00379727-109-27334
Abstract
Rats receiving a thiamine-free diet and with coprophagy prevented were administered thiamine by injection directly into the cecum. Lack of growth response indicated little or no absorption of the injected thiamine from the large intestine. Recovery from feces of the injected thiamine showed a loss equivalent to approximately 4 [mu]g/day. It has been concluded that this represents the rate of destruction of thiamine in the large intestine. The inclucion of penicillin in the diet did not alter the absorbability nor did it affect the rate of destruction of thiamine in the large intestine.Keywords
This publication has 3 references indexed in Scilit:
- Synthesis of Thiamine in the Digestive Tract of the RatJournal of Nutrition, 1961
- The Mechanism of the Thiamine-Sparing Effect of Penicillin in RatsJournal of Nutrition, 1960
- Synthesis of vitamin B1 by intestinal bacteria of the ratBiochemical Journal, 1938