Hemoglobins, XLI. The Embryonic Hemoglobins of Mammal. A New Hemoglobin, Hemoglobin Heide II (Hb HeII: α2ϑ2), and Demonstration of the Hemoglobin Structure of Gower I (ζ2ε2) in the Pig Embryo

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Abstract
A new Hb is described. The Hb of pig embryonic erythrocytes are separated by DEAE-Cephacel chromatography. In addition to a small amount of adult Hb, 4 embryonic Hb are obtained. Each of the Hb components is analyzed by globin and Hb electrophoresis on polyacrylamide gels. Two of these Hb are previously described as Hb Gower II (.alpha.2 .epsilon.2) and Heide I (.zeta.2 .vtheta.2). A tetrameric Hb consisting of .alpha. and .vtheta. chains was detected. This new Hb is named, in analogy, as Hb Heide II (.alpha.2, .vtheta.2). The other Hb tetramer was unequivocally identified as .zeta.2 .epsilon.2. This structure corresponds to Gower I which is only suggested in the human embryo.