Abstract
Annual surveys over a 10-year period, together with individual chemotherapy (tryparsamide) of all positives and follow-up observations of these cases, have proven most effective in controlling sleeping sickness. These methods compare favorably with those involving protective clearing of infested areas and mass treatment, and need far less personnel. Results are improved when diagnosis and treatment are made at earlier stages of the disease and annual inspections give this opportunity. Children are also more readily cured than are adults and are far less apt to develop resistant strains of trypanosomes during the course of treatment.

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