An unusually facile SnAr 14-membered biaryl ether macrocyclization reaction suitable for preparation of the cycloisodityrosine subunit of bouvardin, deoxybouvardin and related agents

This publication has 35 references indexed in Scilit:

• Design, synthesis and evaluation of bouvardin, deoxybouvardin and RA-I-XIV pharmacophore analogs
  Bioorganic & Medicinal Chemistry, 1994
• Total synthesis of cycloisodityrosine, RA-VII, deoxybouvardin, and N29-desmethyl-RA-VII: Identification of the pharmacophore and reversal of the subunit functional roles
  Journal of the American Chemical Society, 1993
• Antitumor Substtance from Higher Plants
  HETEROCYCLES, 1993
• Synthesis of N29-desmethyl RA-VII. Identification of the pharmacophore of RA-I-VII and deoxybouvardin and reassignment of the subunit functional roles
  The Journal of Organic Chemistry, 1992
• Evaluation of bouvardin, deoxybouvardin, and RA-I - RA-VII partial structures: reassignment of the pharmacophore
  Bioorganic & Medicinal Chemistry Letters, 1991
• Studies on antitumor cyclic hexapeptides RA obtained from Rubiae Radix, Rubiaceae. VI Minor antitumor constituents.
  CHEMICAL & PHARMACEUTICAL BULLETIN, 1986
• Studies on the antitumor cyclic hexapeptides obtained from Rubiae radix.
  CHEMICAL & PHARMACEUTICAL BULLETIN, 1983
• The Synthesis of Diphenyl Ethers Having Tyrosine Moiety
  HETEROCYCLES, 1983
• High-yield benzyne synthesis of diaryl ethers
  The Journal of Organic Chemistry, 1982
• Bouvardin and deoxybouvardin, antitumor cyclic hexapeptides from Bouvardia ternifolia (Rubiaceae)
  Journal of the American Chemical Society, 1977