THE MECHANISM OF THE ANTAGONISM BY NALOXONE OF ACUTE ALCOHOL INTOXICATION
Open Access
- 1 November 1981
- journal article
- Published by Wiley in British Journal of Pharmacology
- Vol. 74 (3) , 514-516
- https://doi.org/10.1111/j.1476-5381.1981.tb10458.x
Abstract
Naloxone lowers blood‐ethanol concentration and causes a simultaneous reversal of the disturbances in the redox states of the hepatic nicotinamide‐adenine dinucleotide (phosphate) couples in acutely‐ethanol‐intoxicated rats. It is suggested that these effects of naloxone form the basis of its antagonism of acute alcohol intoxication.Keywords
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