The structure of vacidin A, an aromatic heptaene macrolide antibiotic. II. Stereochemistry of the antibiotic.

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Abstract
On the basis of coupling constants and rotating frame nuclear Overhauser effect spectroscopy of vacidin A methoxycarbonylmethylamide, the stereochemistry of the antibiotic was established. The configuration of the aglycone was determined as (3R,7R,9R,11S,13S,15R,17S,18R,19S,21R,36S,37R,38S). The aminosugar constituent of the antibiotic was identified as .beta.-(D)-mycosamine. The chiral center at C-41 remains to be assigned.