The binding of oestradiol‐17ß to human spermatozoa — an electron microscope autoradiographic study
Open Access
- 1 December 1981
- journal article
- research article
- Published by Wiley in International Journal of Andrology
- Vol. 4 (1-6) , 304-313
- https://doi.org/10.1111/j.1365-2605.1981.tb00714.x
Abstract
The location of steroid binding sites with specificity for oestradiol-17ß at an ultrastructural level has been examined on human spermatozoa by electron microscope autoradiography. About 75% of the 438 grains produced by 3H-oestradiol-17ß, and counted on electron microscope autoradiographs, were found over the plasma membrane or within 1000 Å of it. This study provides evidence suggesting that the plasma membrane is a site of action of oestradiol-17β in human spermatozoa.Keywords
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