The Inverse Relation between Fish Consumption and 20-Year Mortality from Coronary Heart Disease

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Abstract
The low death rate from coronary heart disease among the Greenland Eskimos is ascribed to their high fish consumption. The relationship between fish consumption and coronary heart disease was investigated in a group of men in the town of Zutphen, the Netherlands. Information about the fish consumption of 852 middle-aged men without coronary heart disease was collected in 1960 by a careful dietary history obtained from the participants and their wives. During 20 yr of follow-up 78 men died from coronary heart disease. An inverse dose-response relation was observed between fish consumption in 1960 and death from coronary heart disease during 20 yr of follow-up. This relation persisted after multiple logistic-regression analyses. Mortality from coronary heart disease was > 50% lower among those who consumed at least 30 g of fish per day than among those who did not eat fish. The consumption of as little as 1 or 2 fish dishes per week may be of preventive value in relation to coronary heart disease.