Evolution of alu family repeats since the divergence of human and chimpanzee
- 1 December 1985
- journal article
- research article
- Published by Springer Nature in Journal of Molecular Evolution
- Vol. 22 (4) , 316-322
- https://doi.org/10.1007/bf02115687
Abstract
The DNA sequences of three members of the Alu family of repeated sequences located 5′ to the chimpanzee α2 gene have been determined. The base sequences of the three corresponding human Alu family repeats have been previously determined, permitting the comparison of identical Alu family members in human and chimpanzee. Here we compare the sequences of seven pairs of chimpanzee and human Alu repeats. In each case, with the exception of minor sequence differences, the identical Alu repeat is located at identical sites in the human and chimpanzee genomes. The Alu repeats diverge at the rate expected for nonselected sequences. Sequence conversion has not replaced any of these 14 Alu family members since the divergence between chimpanzee and human.Keywords
This publication has 36 references indexed in Scilit:
- Isolation and nucleotide sequence analysis of the β-type globin pseudogene from human, gorilla and chimpanzeeJournal of Molecular Biology, 1984
- A Gradient of Sequence Divergence in the Human Adult α-Globin Duplication UnitsScience, 1984
- The structure of the human zeta-globin gene and a closely linked, nearly identical pseudogeneCell, 1982
- The deletion in a type of δ0-β0-thalassaemia begins in an inverted AluI repeatNature, 1982
- The Alu Family of Dispersed Repetitive SequencesScience, 1982
- A gene deletion ending at the midpoint of a repetitive DNA sequence in one form of hereditary persistence of fetal haemoglobinNature, 1982
- Base sequence studies of 300 nucleotide renatured repeated human DNA clonesJournal of Molecular Biology, 1981
- Organization and evolutionary progress of a dispersed repetitive family of sequences in widely separated rodent genomesJournal of Molecular Biology, 1981
- Partial deletion of the α-globin structural gene in human α-thalassaemiaNature, 1980
- A study of the evolution of repeated DNA sequences in primates and the existence of a new class of repetitive sequences in primatesJournal of Molecular Biology, 1979