Adenovirus 5 Fibers Mutated at the Putative HSPG-binding Site Show Restricted Retargeting with Targeting Peptides in the HI Loop
Open Access
- 1 April 2007
- journal article
- Published by Elsevier in Molecular Therapy
- Vol. 15 (4) , 741-749
- https://doi.org/10.1038/sj.mt.6300094
Abstract
No abstract availableKeywords
This publication has 32 references indexed in Scilit:
- The influence of adenovirus fiber structure and function on vector development for gene therapyMolecular Therapy, 2005
- Reduction of Natural Adenovirus Tropism to Mouse Liverby Fiber-Shaft Exchange in Combination with both CAR- andαv Integrin-BindingAblationJournal of Virology, 2003
- Replication-Deficient Human Adenovirus Type 35 Vectors for Gene Transfer and Vaccination: Efficient Human Cell Infection and Bypass of Preexisting Adenovirus ImmunityJournal of Virology, 2003
- CAR- or αv integrin-binding ablated adenovirus vectors, but not fiber-modified vectors containing RGD peptide, do not change the systemic gene transfer properties in miceGene Therapy, 2002
- Combined transductional and transcriptional targeting improves the specificity of transgene expression in vivoNature Biotechnology, 2001
- CAR-binding ablation does not change biodistribution and toxicity of adenoviral vectorsGene Therapy, 2001
- HCAR and MCAR: The human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackievirusesProceedings of the National Academy of Sciences, 1997
- Isolation of a Common Receptor for Coxsackie B Viruses and Adenoviruses 2 and 5Science, 1997
- Crystal structure of the receptor-binding domain of adenovirus type 5 fiberprotein at 1.7 Å resolutionStructure, 1994
- Integrins αvβ3 and αvβ5 promote adenovirus internalization but not virus attachmentCell, 1993