Assessment of the Methods Available for the Determination of Carbon Monoxide in Blood

Publisher Website
Google Scholar
Abstract
Experimental evaluation of methods for assessing the carboxyhemoglobln (COHb) content in blood using gas chromatography, UV-visible spectrophotometry (three methods), and magnetic circular dichroism (MCD) has been made. From the point of view of measurements where the COHb content is low (et al. (7) emerges as the most satisfactory. MCD analysis, however, is potentially considerably simpler, not requiring chemical pretreatment of the blood, and provided that analysis time can be improved, is likely to replace the spectrophotometric method as the method of choice.