Developmentally regulated alternative splicing of brain myelin‐associated glycoprotein mRNA is lacking in the quaking mouse
- 23 May 1988
- journal article
- Published by Wiley in FEBS Letters
- Vol. 232 (2) , 323-327
- https://doi.org/10.1016/0014-5793(88)80762-2
Abstract
Evidence is presented that expression of the two myelin-associated glycoprotein mRNAs is developmentally regulated in mouse brain. In quaking mouse, the mRNA without a 45-nucleotide exon portion was scarcely expressed throughout development. We conclude that the mechanism of splicing out the 45-nucleotide exon portion is lacking in quaking mouseKeywords
This publication has 15 references indexed in Scilit:
- [57] Sequencing end-labeled DNA with base-specific chemical cleavagesPublished by Elsevier ,2004
- Chromosomal Location of the Mouse Gene that Encodes the Myelin-Associated GlycoproteinsJournal of Neurochemistry, 1988
- Myelin-Associated Glycoprotein in the Central and Peripheral Nervous System of Quaking MiceJournal of Neurochemistry, 1987
- The amino acid sequences of the myelin-associated glycoproteins: homology to the immunoglobulin gene superfamilyThe Journal of cell biology, 1987
- Abnormal Expression of the Myelin‐Associated Glycoprotein in the Central Nervous System of Dysmyelinating Mutant MiceJournal of Neurochemistry, 1985
- Myelin-Associated Glycoprotein in Development and DiseaseDevelopmental Neuroscience, 1983
- [10] 5′-32P labeling of RNA and DNA restriction fragmentsPublished by Elsevier ,1980
- Isolation of biologically active ribonucleic acid from sources enriched in ribonucleaseBiochemistry, 1979
- ANOMALIES OF MYELIN‐ASSOCIATED GLYCOPROTEINS IN‘QUAKING MICEJournal of Neurochemistry, 1974
- Mutant Mice (Quaking and Jimpy) with Deficient Myelination in the Central Nervous SystemScience, 1964