Time-resolved coherent anti-Stokes Raman scattering microscopy: Imaging based on Raman free induction decay
- 4 March 2002
- journal article
- Published by AIP Publishing in Applied Physics Letters
- Vol. 80 (9) , 1505-1507
- https://doi.org/10.1063/1.1456262
Abstract
A time-resolved coherent anti-Stokes Raman scattering (CARS) microscope allows three-dimensional imaging based on Raman free induction decay of molecular vibration with no requirement for labeling of the sample with natural or artificial fluorophores. A major benefit of the technique is the capability to completely remove nonresonant coherent background signal from the sample and the solvent, and thus increasing the detection sensitivity of CARS microscopy significantly.Keywords
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