Effects of Varying the Output of a Mechanical Left Ventricle on the Circulation in the Dog

Publisher Website
Google Scholar
Abstract
A pump with independent controls of rate and stroke volume was substituted for the left ventricle in dogs. Mean arterial pressure was found to be a function of minute pump output, rather than rate or stroke volume. The output of the intact right ventricle kept pace with that of the pump. This was accomplished almost entirely by a stroke volume increase rather than a rate change. Stepwise increases and decreases in pump output produced parabolic pressure [long dash]output curves in both pulmonary and systemic arteries which paralleled each other and which were characterized by larger pressure increments and decrements at lower outputs. Negligible changes in venous pressure occurred when the right ventricle was functioning effectively.

This publication has 1 reference indexed in Scilit: