Computer modelling of antifolate inhibition of folate metabolism using hybrid functional petri nets
- 1 June 2006
- journal article
- Published by Elsevier in Journal of Theoretical Biology
- Vol. 240 (4) , 637-647
- https://doi.org/10.1016/j.jtbi.2005.11.001
Abstract
No abstract availableKeywords
This publication has 18 references indexed in Scilit:
- Pemetrexed in Malignant Pleural MesotheliomaClinical Cancer Research, 2005
- A Mathematical Model of the Folate CycleJournal of Biological Chemistry, 2004
- Marked suppression of the activity of some, but not all, antifolate compounds by augmentation of folate cofactor pools within tumor cellsBiochemical Pharmacology, 2001
- E-CELL: software environment for whole-cell simulation.Bioinformatics, 1999
- Immunosuppressive properties of methotrexate: apoptosis and clonal deletion of activated peripheral T cells.Journal of Clinical Investigation, 1998
- Biochemistry and pharmacology of glycinamide ribonucleotide formyltransferase inhibitors: LY309887 and lometrexolInvestigational New Drugs, 1996
- Immunoreactive dUMP and TTP pools as an index of thymidylate synthase inhibition; effect of tomudex (ZD1694) and a nonpolyglutamated quinazoline antifolate (CB30900) in L1210 mouse leukaemia cellsBiochemical Pharmacology, 1996
- SPICE2 network thermodynamic simulation of antifolate effects on purine and pyrimidine biosynthesis: Exploring the role of tetrahydrofolate cofactor depletion versus dihydrofolate feedback inhibitionComputers & Mathematics with Applications, 1990
- Biochemical effects of a quinazoline inhibitor of thymidylate synthetase, N-(4-(N-((2-amino-4-hydroxy-6-quinazolinyl)methyl)prop-2-ynylamino)benzoyl)-l-glutamic acid (CB3717), on human lymphoblastoid cellsBiochemical Pharmacology, 1983
- Exact stochastic simulation of coupled chemical reactionsThe Journal of Physical Chemistry, 1977