Histamine Concentration in Blood, Milk, and Urine of Dairy Cattle

Open Access
Publisher Website
Google Scholar
Abstract
Blood histamine values determined fluorimetrically in 19 growing Holstein heifers, from birth to 45 weeks, averaged .29 [mu]g/ml (range for an 11-14 week period, .25 [plus or minus] .08 to .36 [plus or minus] .09 [mu]g/ml). Eight bulls showed similar average blood values of .30 [mu]g/ml (range, .25 [plus or minus] .06 to .36 [plus or minus] .09 [mu]g/ml). Blood levels during this rapid growth period showed little change, values being slightly lower during the earlier weeks. Blood histamine concentration of 5 animals sampled at 6 hour intervals for 3 days indicated little diurnal variation. Such repetitive sampling was, however, associated with a progressive increase in histamine level. Twenty-five milk samples from 15 cows were analyzed for histamine, the mean concentration being .51 [plus or minus] .34 [mu]g/ml. When the fluorimetric histamine procedure was applied to urine, 4 samples from heifers fed alfalfa-grass hay showed a mean concentration of 1.10 [plus or minus] .91 [mu]g/ml while 4 samples from animals fed alfalfa-grass silage were 19.53 [plus or minus] 16.42 [mu]g/ml. These concentrations averaged about 20 to 30 times those found in blood.

This publication has 6 references indexed in Scilit: