Interferon induces pulmonary cysts in A2G mice.
- 1 December 1984
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 81 (24) , 7937-7940
- https://doi.org/10.1073/pnas.81.24.7937
Abstract
Suckling A2G mice were treated for the 1st wk of life with either partially purified or electrophoretically pure mouse .alpha./.beta. interferon. All mice subsequently developed multiple large pulmonary cysts. The lesions were never found in interferon-treated Swiss mice and only very infrequently in interferon-treated BALB/c or F1 Swiss/A2G mice. A brief exposure of suckling A2G mice to .alpha./.beta. interferon can result in a severe disease that is determined by the mouse genotype.This publication has 15 references indexed in Scilit:
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