Comparative Histological Study of Mini Pig Skin After Chemical Peel and Dermabrasion

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Abstract
• Although individual studies of the histological changes after chemical peel and dermabrasion have been reported, there has not been a comparative study of these modalities in the same animal model. Using the mini pig, whose skin most closely resembles human skin, a study was performed of histological changes 24 hours to 16 weeks after dermabrasion and chemical peel. A considerable increase in thickness of the new collagen layer was noted after chemical peel in contrast to that seen in skin after dermabrasion. The skin surface after chemical peel appeared smoother after 16 weeks, suggesting that chemical peel may be a more effective modality for treatment of the fine wrinkles of aging skin. (Arch Otolaryngol 103:271-277, 1977)

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