QUANTITATION OF LYMPHOCYTE-T SUBSETS IN HUMAN BRONCHUS MUCOSA

Publisher Website
Google Scholar
Abstract
Cells were isolated from human bronchus mucosa and characterized according to a surface marker for sheep erythrocytes (T cells), to the presence of membrane-associated Ig (B cells) and to the capacity to phagocytose latex particles (macrophages). T lymphocytes were further characterized according to their capacity to bind to the Fc fragment of IgG, IgM and IgA (T.gamma., T.mu. and T.alpha. cells, respectively). Less t.alpha. cells were found in acutely inflamed mucosa than in mucosa obtained from patients with chronic inflammatory, or neoplastic disease (P = < 0.001).