Modulation of Cell Behavior In Vitro by the Substratum in Fibroblastic and Leukemic Mouse Cell Lines
- 1 September 1972
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 69 (9) , 2469-2473
- https://doi.org/10.1073/pnas.69.9.2469
Abstract
Fibroblastic and leukemic mouse cell lines were cultivated on a bovine serum albumin polymer covered with basic or acidic substances. Contact inhibition of fibroblast movement (cell overlapping) and division varied depending on prior treatment of the albumin polymer. The leukemic cells, which normally grow in suspension, attached and spread out on the polymers and could be carried as a monolayer. Preparation of surfaces capable of modulating different parameters of cell behavior in vitro is thus possible.Keywords
This publication has 14 references indexed in Scilit:
- Topoinhibition and Serum Requirement of Transformed and Untransformed CellsNature, 1970
- GROWTH CHARACTERISTICS OF VIRUS-TRANSFORMED CELLSThe Journal of Experimental Medicine, 1970
- Flattening, movement and control of division of epithelial-like cellsJournal of Cellular Physiology, 1970
- The effect of pH on the propagation of the diploid cell WI-38 in galactose mediumJournal of Cellular Physiology, 1967
- Relationship between DNA synthesis and cell density in normal and virus-transformed cellsInternational Journal of Cancer, 1967
- Dissociation between inhibition of movement and inhibition of division in RSV transformed human fibroblastsExperimental Cell Research, 1967
- Principles of Cell Motility: The Direction of Cell Movement and Cancer InvasionNature, 1965
- The initiation of cell division in a contact‐inhibited mammalian cell lineJournal of Cellular and Comparative Physiology, 1965
- PRODUCTION AND CHARACTERIZATION OF MULTIPLE-LAYERED POPULATIONS OF ANIMAL CELLSThe Journal of cell biology, 1965
- Histones and Basic Polyamino Acids Stimulate the Uptake of Albumin by Tumor Cells in CultureScience, 1965