Thromboangiitis Obliterans — An Autoimmune Disorder?

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Abstract
Since Leo Buerger reported his classic studies in 1908,1 clinicians and investigators have been interested in thromboangiitis obliterans (Buerger's disease), which has several characteristic features. No other occlusive peripheral arterial disease has the same predisposition for young men, affects the small and medium-sized arteries of the wrist and hand with almost the same frequency as those of the leg and foot, and is accompanied so often (in about 40 per cent of cases) by superficial thrombophlebitis.Thromboangiitis obliterans is a segmental inflammatory panarteritis or panphlebitis (or both) of the small and medium-sized arteries and veins, involving chiefly vessels of the . . .

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