Nucleotide sequence of the xanthine guanine phosphoribosyl transferase gene ofE. coli

Abstract
The nucleotide sequence of the gpt gene coding for the enzyme xanthine guanine phosphoribosyl transferase has been determined. The gene codes for a protein of molecular weight 16,950. The construction of deletions in the gpt gene which can be used for the genetic analysis of mutations in the gpt gene, is described.