Traumatic Shock

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Abstract
Plasma prothrombin activity declines during hemorrhagic shock in dogs. The decline in prothrombin activity is attributable in part to a reduction in prothrombin conversion factors. The decline in activity is greatest in animals which show a poor tolerance to the shock state. Prothrombin regeneration is markedly delayed after a period of hemorrhagic shock. This is further evidence that the hepatic injury persists long after the correction of the blood volume deficit. These data do not indicate to what extent the lowered prothrombin activity contrib-utes to intestinal bleeding in exptl. shock.