Indirect Coupling of the 2(1H)‐pyrazinone Scaffold with Various (oligo)‐saccharides via “click chemistry”: en route towards Glycopeptidomimetics
- 28 December 2004
- journal article
- research article
- Published by Wiley in QSAR & Combinatorial Science
- Vol. 23 (10) , 915-918
- https://doi.org/10.1002/qsar.200420049
Abstract
The indirect coupling via a 1,2,3‐triazole ring system, of the 2(1H)‐pyrazinone scaffold with various saccharides is described. A microwave‐enhanced Cu(I)‐catalyzed Huisgen [2+3] dipolar cycloaddition reaction is applied. This opens the way for the generation of an interesting new class of glycopeptidomimetics.Keywords
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